Patient-derived xenograft models reveal intratumor heterogeneity and temporal stability in neuroblastoma
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چکیده
منابع مشابه
Characterization of genetic intratumor heterogeneity in colorectal cancer and matching patient‐derived spheroid cultures
Patient-derived in vitro cultures of colorectal cancer (CRC) may help guide treatment strategies prior to patient treatment. However, most previous studies have been performed on a single biopsy per tumor. The purpose of this study was to analyze multiple spatially distinct biopsies from CRCs and see how well intratumor heterogeneity (ITH) was recapitulated in matching patient-derived spheroids...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2018
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-18-0527